Who Do We Serve?
Ovarian Cancer
High-Grade Serous Ovarian Cancer (HGSOC)
Ovarian cancer is often called the “silent killer” because over 70% of cases are diagnosed at an advanced stage, leading to a 5-year survival rate of only about 30% in late-stage cases, compared to over 90% when caught early.
OncoGaze™ detects HRD status at biopsy, helping connect Ovarian Cancer patients to the right treatments, faster.
Ovarian Cancer Today
Ovarian cancer is often called the “silent killer” because over 70% of cases are diagnosed at an advanced stage, leading to a 5-year survival rate of only about 30%.
70%
Currently, 70% of Ovarian Cancer patients are diagnosed at a late stage in their disease.
30%
This corresponds to a 30% 5-year survival rate.
90%
With earlier detection and access to the correct therapies, the 5-year survival rate for Ovarian Cancer can increase to 90%*
19,700
cases/year U.S.
313,000
cases/year worldwide
50%
HRD is prevalent in 50% of cases of Ovarian Cancer
HRD is a key biomarker in ovarian cancer and is essential for matching patients to appropriate targeted therapies.
Who should get tested for HRD?
All Ovarian Cancer patients should be tested for HRD.
HRD (Homologous Recombination Deficiency) is prevalent in over 50% of cases of Ovarian Cancer. Testing for HRD helps determine if a tumor is deficient in DNA repair mechanisms, which can impact treatment decisions. OncoGaze™ HRD testing can be done from a routine biopsy slide, identifying morphological indicators of HRD invisible to the human eye. A positive HRD result suggests that a tumor may be more sensitive to PARP inhibitors.
Acurion’s OncoGaze detects HRD status in minutes, which can direct patients to the relevant treatment weeks ahead of standard NGS testing.
Why does this matter?
In ovarian cancer, initiating the wrong treatment while awaiting next-generation sequencing (NGS) results can compromise outcomes. Preemptive therapy may delay access to targeted treatments or render patients ineligible for more effective options later on. Early genomic insight is critical to align first-line therapy with tumor biology—when it matters most.
Acurion's OncoGaze™ delivers fast, accurate genomic insights from pathology slides—accelerating access to targeted therapy for ovarian cancer patients.
“As a gynecologic pathologist and Chair of a large Department of Pathology in a major academic university, I am well aware of the importance, especially for patients with ovarian cancer, and notorious challenges, of HRD molecular testing. HRD testing is much more difficult and complex than many other genomic tests currently in clinical use. The oncology community, as well as most large academic medical centers, must rely on send-outs, which are expensive, require a lot of tissue, have slower turn-around-times, and are subject to higher test failure rates than other molecular tests.
Dr. Alexandrov and his colleagues at Acurion have picked absolutely the right molecular test to improve upon with their innovative approach, replace with an AI test AI frameworks an approach that unlocks the power of routine H&E stained slides to detect HRD, as a welcome improvement on current workflows. I see our patients benefitting from this new approach that will greatly increase the value and importance of our pathology reports.”

Russell Broadus, MD/PhD
Chair of the Department of Pathology & Laboratory MedicineJoe W. and Evelyn Grisham Distinguished Professorship
University of North Carolina School of Medicine
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